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Rams vs. 49ers predictions, odds, time: 2025 NFL Week 5 Thursday Night Football picks by advanced model
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 39-20 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

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San Francisco 49ers at LA Rams odds, picks and predictions
Saints vs. Rams Prediction, Odds, Spread, Injuries, Trends for NFL Week 9
What NFL games are on today? Week 9 TV channels, Sunday schedule
Six teams that had Week 8 off return to action in Week 9, and even with four others heading into a bye this week, the Nov. 2 slate will have one more game than the schedule one week earlier.

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Steelers vs. Colts score: Six Indianapolis turnovers aid Pittsburgh to 27-20 upset win
Jaylen Warren's second TD of the day gives the Steelers a sizable lead to open the fourth quarter.

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Where to watch Steelers vs. Colts NFL Week 9 game today on free streams, TV
3 predictions for Kansas City Chiefs' rivalry matchup vs. Buffalo Bills in Week 9

Rams vs. 49ers prediction: High-octane L.A. offense looking to keep rolling against banged-up San Francisco

The NFC West is a crowded race to start the 2025 NFL season, as expected, but two of the teams atop the division are in very different places. Both the Los Angeles Rams and San Francisco 49ers sport 3-1 records entering Week 5, which they'll kick off on "Thursday Night Football." Yet only one is operating with momentum.

49ers vs. Rams predictions, picks and best bets for NFL Thursday Night Football: NFC West rivalry in primetime

These coaches are friends who joined the division at the same time, are considered offensive geniuses and have had successful tenures as coaches of their respective teams. When they meet on NFL Thursday Night Football, McVay’s Rams are in much better shape when it comes to team health and availability.

49ers-Giants roundtable: Can depleted defense stop Dart? Trade deadline predictions?

The San Francisco 49ers face the New York Giants needing a win to rally amid another season threatening to be derailed by injuries. Here's what our NFL coverage team expects.
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What are your Rams-Saints final score predictions?

What are your Los Angeles Rams (5-2) versus the New Orleans Saints (1-7) final score predictions? I am picking the Rams in this one, and I want to keep my prediction grounded, but in theory, this game could (and maybe should?) get out of hand in favor of the Rams, but I’ll keep my prediction Rams 27, Saints 10.

49ers at Texans prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats

Mac Jones continues under center for the 49ers (5-2) when they travel to Houston for a Sunday afternoon tilt against the Texans (2-4). Despite being one of the most banged-up teams in the NFL, San Francisco sits tied atop the NFC West with the Seahawks and the Rams.
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