The ancient biochemical 5-hydroxytryptamine—also known as 5-HT and serotonin—has been controlled through evolution to be used widely across the plant and animal kingdoms. 5-HT is used by mammals as a ...

Shanghai Institutes for Biological Sciences and Shanghaitech University have identified dopamine D2 receptor and/or 5-HT receptor agonists reported to be useful for the treatment of depression and ...

Receptors for a specific form of serotonin is widely distributed in the bladder urothelium, investigators noted. Serotonin (5-hydroxytryptamine [5-HT]) is one of several important neurotransmitters ...

Shionogi & Co. Ltd. has synthesized spiroheterocycle derivatives acting as 5-HT2A and 5-HT2C receptor antagonists and/or inverse agonists reported to be useful for the treatment of neurodegeneration.

AbbVie (ABBV) announced that it has completed its acquisition of Gilgamesh Pharmaceuticals’ lead investigational candidate, bretisilocin. Bretisilocin is a novel, short-acting serotonin 5-HT2A ...

AbbVie has announced that it has completed its acquisition of Gilgamesh Pharmaceuticals' lead investigational candidate, ...

A perspective article published in Psychedelics by Prof. Xiaohui Wang and colleagues examines how psychedelic substances profoundly reshape the perception of time, offering unprecedented insights into ...

Serotonergic psychedelics, such as psilocybin and LSD, are also commonly referred to as hallucinogens because at higher "trip-inducing" doses (as opposed to microdoses), these drugs typically trigger ...

Serotonergic psychedelics, such as psilocybin and LSD, are also commonly referred to as hallucinogens because at higher "trip-inducing" doses (as opposed to microdoses), these drugs typically trigger ...