Beyond AFP: Emerging Biomarkers for Hepatocellular Carcinoma Diagnosis, Prediction, and Follow-up —Serum alpha-fetoprotein is the standard clinical biomarker for hepatocellular carcinoma.

The most commonly used tumor marker is AFP. Doctors use tumor markers to detect ... Research suggests the detection rate of HCC increases when OPN testing is combined with AFP and other biomarkers.

Once a biomarker test exists, Nghiem envisions it being used to identify who should receive ICIs, or help figure out why a patient didn’t respond to an ICI as expected. In these cases, he said, if the ...