Researchers have discovered a plausible evolutionary setting in which nucleic acids—the fundamental genetic building blocks of life—could enable their own replication, possibly leading to life ...

Nucleic acids may be labeled at their 3’ end, 5’ end, or throughout the molecule, depending on the desired application. Myriad of enzymatic or chemical methods are utilized to generate nucleic ...

By sensing viral nucleic acids and producing type I interferons, plasmacytoid dendritic cells (pDCs) are key mediators of antiviral immunity. But pDCs might also contribute to autoimmune disease ...

A plethora of chemical or enzymatic methods are available to generate nucleic acids such as those labeled with fluorophores, enzymes and radioactive phosphates, or nucleotides modified with ...

Summary Fluorescent labeling is the process of covalently attaching fluorescent groups to molecules such as proteins and nucleic acids. Such processes are typically accomplished using derivatives of ...

Purines in Cellular Metabolism In addition to their role in nucleic acids, purines are involved in various cellular metabolic processes. Purine nucleotides, such as ATP and GTP, serve as energy ...

Scientists visualize how a vital hepatitis C virus protein moves along its nucleic acid substrate Date: January 4, 2010 Source: Rockefeller University Summary: By taking three conformational ...

The central dogma or the directional flow of genetic information from a deoxyribose nucleic acid (DNA) template to a ribose nucleic acid (RNA) transcript, and finally into a functional protein, is ...