The proton gradients that power respiration are as universal as the genetic code itself, giving an insight into the origin of life and the singular origin of complexity.

TMC207 inhibits the proton pump of mycobacterial ATP synthase, a critical enzyme in the synthesis of ATP for Mycobacterium tuberculosis. Resistance is achieved through mutations at position 63 or ...

The production of ATP relies on a vital enzyme known as ATP synthase, a process occurring within the mitochondria of eukaryotic cells found in fungi, animals, and plants. This is why the ...

Mitochondrial genome contributes polypeptide subunits to the five enzyme complexes that comprise ... which is harnessed by the ATP synthase to drive the formation of ATP.