News

KCTD1 regulation of Adenylyl cyclase type 5 adjusts striatal cAMP signaling. Journal: Proceedings of the National Academy of Sciences of the United States of America Published: 2024-10-22 DOI: ...
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into -related dyskinesia Journal: Nature Structural & Molecular Biology Published: 2024-04-08 DOI: 10.1038/s41594-024-01263-0 ...
Bayer announced today the start of ALPINE-1 study, a Phase II clinical trial with BAY3283142, an investigational soluble guanylate cyclase (sGC) activator, i ...
MLN0264, an investigational antiguanylyl cyclase C (GCC) antibody-drug conjugate (ADC), in patients (pts) with advanced gastrointestinal (GI) malignancies: Phase I study.
Soluble guanylate cyclase activator vericiguat prevents anthracycline-mediated cardiotoxicity and sarcopenia through cGMP-NLRP3-cytokine pathway: Potential application in patients with cancer.