Advil (ibuprofen) and Aleve (naproxen) are very similar over-the-counter (OTC) medications, both members of a group called non-steroidal anti-inflammatories (NSAIDs). One important difference is ...

Advil and Aleve are both non-selective NSAIDs, meaning that they can bind to both the COX-1 and COX-2 enzymes. Differences. Advil and Aleve differ somewhat in terms of their intended use.

Ibuprofen or Aleve isn’t recommended because it causes liver and kidney damage. So, we bought Tylenol, and he used this medication instead of his usual. But his pain only got worse.

Tylenol vs. Advil vs. Aleve. Advil (ibuprofen) and Aleve (naproxen) are non-steroidal anti-inflammatory drugs. They work by inhibiting an enzyme in the body called cyclooxygenase, or COX for short.

Ibuprofen (Advil or Motrin), naproxen (Aleve) and aspirin (Bayer or Ecotrin) are common pain relievers that belong to a class of medication called non-steroidal anti-inflammatory drugs (NSAIDs).

Ibuprofen (Advil or Motrin), naproxen (Aleve) and aspirin (Bayer or Ecotrin) are common pain relievers that belong to a class of medication called non-steroidal anti-inflammatory drugs (NSAIDs).

Drugs like ibuprofen can damage our gut lining. Try this instead. Studies have linked nonsteroidal anti-inflammatory drugs, such as ibuprofen, naproxen and aspirin, to serious health effects.

Many are prescription, but of the ones that are nonprescription, ibuprofen is Advil. Motrin also is the same drug. And then you've got Naproxen, which is a different drug.

Naproxen (sold as Aleve), however, does tend to keep pain away for longer than the other NSAIDs — about 12 hours, Dr. McPherson said. Ibuprofen (Advil, Motrin), on the other hand, works for ...

Learn more from WebMD about over-the-counter pain relievers for arthritis, including benefits, possible side effects, and how to avoid overdosing.