A high-yield, one-pot, scalable reaction facilitates the production of biologically relevant amide compounds using less reactive nitrogen-containing heterocyclic compounds and carboxylic acid ...

image: Optimized reaction conditions for amide bond formation in nitrogen-containing heterocyclic compounds using carboxylic acid requires only 4-(N,N-dimethylamino)pyridine N-oxide (DMAPO) and di ...

image: This is a scheme of reaction rate acceleration of amide hydrolysis by inclusion in the self-assembled molecular cage. view more . Credit: NINS/IMS.

Key components of proteins are twisted to boost reactions useful to medicine Date: May 28, 2020 Source: University of Tokyo Summary: In proteins, amino acids are held together by amide bonds.