Why does the rooster crow and the hen does not? This question prompted the scientist Arnold Adolph Berthold to castrate a ...

Prostate cancer progresses from a hormone-sensitive, androgen-dependent stage to a hormone-refractory, androgen-independent tumor. The androgen receptor pathway functions in these androgen ...

But of course, the last few years, really the last decade to decade and a half, has been the advent of what we call, now call ARPIs, or androgen receptor pathway inhibitors. And these are really ...

To enable precision medicine by targeting the androgen pathway, defining androgen-associated sex-biased differentially expressed genes in each cell type is necessary. This will help identify sex ...

An expert discusses how the PEACE III combination of radium-223 and enzalutamide represents an effective treatment option for the limited population of patients who reach first-line metastatic ...

The approval of 3 androgen receptor pathway inhibitors (ARPIs) has given providers novel treatment options for patients with nonmetastatic castration-resistant prostate cancer (nmCRPC) that have ...

Scientists at the University of Michigan Rogel Cancer Center have found an important clue to why some men with advanced ...

Researchers explore role of androgens in shaping sex differences. Chinese Academy of Sciences Headquarters. Journal Nature DOI 10.1038/s41586-024-07291-6 ...

While many patients experience long-term benefits from cancer treatment, some will derive no benefit whatsoever. The study ...