Mutations of apoptosis-related genes lead to tumor formation. Since apoptosis is a complex process involving a large array of genes, and any mutation of apoptosis-related genes may lead to the ...

Prognostic impact of apoptosis-related and DNA repair gene polymorphisms in patients with advanced colorectal cancer treated with capecitabine and oxaliplatin chemotherapy. JCO 26 , 15123-15123 (2008) ...

New data shows Telomir-1 fully reverses STAT1 gene silencing by DNA methylation - a key immune regulator suppressed in cancer - delivering stronger epigenetic effects than Paclitaxel or Rapamycin in ...

Background: The FAS, FAS ligand (FASL) and CASP8 are key regulators for apoptosis and their deregulations play an important role in carcinogenesis.However, the effects of promoter polymorphisms of the ...

Epigenetics involves a series of biological processes that regulate chromatin-mediated DNA templates. 2 Cancer is a ...

A team led by Professor Wang Tao at Tianjin University’s School of Life Sciences has uncovered how the Severe Fever with ...

In previous research they had discovered several genes within a section of the virus called the E3 transcription unit that interfere with apoptosis signaling — the natural pathway of cell death.