British Journal of Cancer - Staurosporine-induced apoptosis and hydrogen peroxide-induced necrosis in two human breast cell lines Skip to main content Thank you for visiting nature.com.

The protein we identified, a sodium-ion channel known as TRPM4, is critical for cancer therapies that promote this type of cell death, called necrosis.” Unlike apoptosis, necrosis strongly ...

Tumor necrosis factor α-induced protein 3-interacting protein 1 (TNIP1) is a ubiquitin-binding protein that is widely expressed, but its function in breast cancer cells remains unknown.

Jan. 13, 2022 — Understanding the basic mechanisms that lead to cell death (apoptosis) is essential for the development of therapies for cancer and other diseases. Scientists have now discovered ...

During apoptosis, a cell is broken up and packaged into small, ... Necrosis happens in response to high temperature or high ... Cancer cells are masters at evading our immune system and avoiding ...

Medical professionals call this type of cancer-driving protein an oncogene, and in cancer like lymphoma, BCL6 sits on DNA near genes that promote apoptosis and then keeps them turned off.

Aug. 14, 2024 — Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in tumor cells. However, tumor cells have the ability to develop strategies to escape ...

Cell death occurs by necrosis or apoptosis. 7–9 These two mechanisms have distinct histologic and biochemical signatures. In necrosis, the stimulus of death (e.g., ischemia) is itself often the ...

A University of Pennsylvania research team has shown that it can kill tumor cells in mice by necrosis, rather than by inducing apoptosis, by giving them alkylating agents that block their energy ...

Scientists have demonstrated a creative new way to kill cancer cells effectively, with few side effects. Gluing two particular proteins together tricks the tumors into destroying themselves.