That's why popular intermittent fasting methods like the 16/8 (fasting for 16 hours and having an 8-hour eating window) are often associated with inducing autophagy, as they meet the minimum hours ...

Dr. Chris Rhodes explains precisely what happens during prolonged fasting — plus, experts weigh in on the downsides and who ...

I totally screwed up intermittent fasting at first. I was hangry all the time, exhausted by […] The post 16/8 Intermittent ...

What’s true is fasting influences autophagy in non-human studies — sometimes, and in a not-well-understood way. We still don’t know much about autophagy in humans, or how to measure it ...

Autophagy is the body’s way of cleaning out damaged cells, in order to regenerate newer, healthier cells. It allows your body to remove the dysfunctional cells.

So exactly how much fasting is required to increase autophagy in humans is completely unknown: influencer claims of 16, 24 or 48 hours are stabs in the dark. This is equally true for supplements.

More information: Sebastian J. Hofer et al, Spermidine is essential for fasting-mediated autophagy and longevity, Nature Cell Biology (2024). DOI: 10.1038/s41556-024-01468-x.

We wanted to further our understanding of how autophagy is involved in the body's metabolic response to fasting. To do so, we evaluated the effects of modulating autophagy in the adipose cells of ...