Since the first demonstration of foreign gene expression in baculovirus in 1983 (ref. 2), the field has seen developments in both the method for forming recombinants and in the type of vector used.

Protein expression systems are notoriously difficult to work with, but a bevy of researchers have found solutions that have facilitated their protein therapeutic work. At ISBiotech’s meeting ...

Baculovirus has emerged as a novel vector for in vitro and in vivo gene delivery due to its low cytotoxicity and non-replication nature in mammalian cells, but the applications of baculovirus in ...

The baculovirus–insect cell expression system—insect cells used in conjunction with the baculovirus expression vector system (BEVS)— remains a crucial technology for manufacturing large and ...

To create a more capacious delivery system, scientists based at the University of Bristol turned to a rod-shaped baculovirus. As a gene therapy vector, the baculovirus offers a valuable trait: It ...

Over the past three decades, baculovirus expression vector system (BEVS) has become one of the most powerful and robust methodologies for recombinant protein production. This system can express ...

The Baculovirus Expression Vector System is a versatile platform for expression of individual recombinant proteins, membrane proteins, virus-like particles and Adeno-associated virus (AAV). In this ...

The baculovirus-insect cell expression system is a potent and adaptable platform for protein production. The robust post-translational modification capabilities and relatively high cell culture ...

Baculovirus transduction is a gene transfer method that uses a moth cell virus for mammalian cells in culture, which results in a high-level prolonged expression. Here we demonstrate that ...

VectorY’s manufacturing capabilities will include a state-of-the-art multi-product GMP facility in the Netherlands, with the capability to deliver suspension based AAV viral vector manufacturing ...

Baculovirus-mediated gene transfer to human and mouse pancreatic islet dissociated cells. Using the recombinant baculovirus BacCMV-GFP, enhanced GFP (EGFP) expression was observed in both primary ...