In 1825 Michael Faraday isolated a sweet-smelling chemical that he dubbed bi-carburet of hydrogen. That molecule, better ...

(Nanowerk News) Tuning the para position of benzene moieties is significant for creating biologically active compounds and optoelectronic materials. Yet, attaching a functional handle specifically at ...

Nonetheless, introducing a boryl group at a specific position on the 6-membered benzene ring has been rather challenging due to the presence of several reactive sites.

Despite being highly useful, multi-substituted benzene derivatives are rather difficult to synthesize due to the lack of selective methods to install different substituents at the desired positions.

This isn’t the first time chemists have wedged open benzene’s ring, Aldridge says. One well-known instance, the Buchner ring expansion, dates to the 19th century.