Perimenopausal women with higher baseline levels of serum bone turnover markers and a lower trabecular bone score are at increased risk for presenting with osteopenia or osteoporosis at 5-year ...

This study aims to assess whether these variations alter gene expression related to bone remodeling and glycation in osteocytes, the primary orchestrators of the bone turnover process. We hypothesized ...

An existing drug that targets senescent, or sleeping cells could provide the answer to treating lower back pain, according to a new study.

Now, Thomas Nickolas and colleagues report that patients with CKD show rapid loss of cortical bone, which is associated with hyperparathyroidism and increased levels of bone remodelling markers.

The 7 key factors beyond calcium for optimal bone health Research from leading institutions worldwide has identified several critical factors that influence bone formation, maintenance, and loss ...

“Most clinical studies investigating biochemical markers of bone turnover (BTM) measured in peripheral blood or bone remodelling assessed in bone biopsies have reported lower bone turnover in ...

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis.

8140 Background: Aminobisphosphonates (aBP) are standard of care for myeloma related bone disease and are recommended every 3-4 weeks. Our previous data suggests altered bone remodeling in ...

A new consensus paper provides an updated evaluation of reference bone turnover markers (BTMs) and newer markers in the diagnosis and management of osteoporosis.

Competitive analysis Primary research Bibliography Exhibit 3-1: The bone remodeling cycle Exhibit 3-2: Comparison of the types of bone turnover marker tests Exhibit 3-3: Selected bone turnover ...

Background: The presence of bone metastases (BMe) alters the balance of bone remodeling and, consequently, levels of bone turnover markers (BTM). Increased levels of these biomarkers are related to ...