By Jeyashree Sundaram, MBA. Cyclic adenosine 3,5-monophosphate (cAMP) is a cyclic nucleotide that serves as a vital second messenger in several signaling pathways.

This study was performed to investigate the signaling pathway that mediates cyclic AMP (cAMP)-induced inhibition of histone deacetylase 8 (HDAC8) degradation, and the effect and underlying ...

Similar to the MAPK-associated pathway, 3′–5′-cyclic adenosine monophosphate (cAMP)-associated pathways are also coupled to activation of neurotransmitter receptors, and modulate cellular ...

Cyclic dinucleotides (CDNs) are secondary messengers used by prokaryotic and eukaryotic cells. In mammalian cells, cytosolic CDNs bind STING (stimulator of IFN gene), resulting in the production of ...

Striatal neuromodulation through G-protein-coupled receptors (GPCRs) regulates complex voluntary motor actions, involving decision-making, learning, and action selection. The dorsal striatum ...

Bear bile powder inhibits the release of NLRP3 by activating the cAMP/PKA/CREB signaling pathway to treat dextran sulfate sodium-induced colitis in mice ...

Cyclic adenosine monophosphate (cAMP) is one of the most important signaling molecules in virtually all cell types and organisms. We describe cAMPr, a new single-wavelength cAMP sensor.