Researchers led by MENG Wenxiang from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have shown that knocking out of the calmodulin-regulated spectrin ...

Microtubule plus ends and minus ends accumulate specific sets of proteins that can regulate microtubule dynamics, connect microtubules to cellular structures and recruit signalling molecules that ...

Combined structural and microscopy approaches provide a model for how CAMSAP proteins recognize microtubule minus ends through their conserved CCK domains and protect microtubules from ...

In fact, depleting tau made the remaining microtubules more stable, instead of less. This alters our basic understanding about tau. “We found that tau does not stabilize the neuron’s microtubules. The ...

Microtubules Negatively Regulate Insulin Secretion in Pancreatic β Cells. Developmental Cell , 2015; 34 (6): 656 DOI: 10.1016/j.devcel.2015.08.020 Cite This Page : ...

BUFFALO, N.Y. -- Neuroscientists at the University at Buffalo have shown in two recently published papers that destabilization of structures called microtubules, intracellular highways that transport ...

Evidence of microtubules’ mechanosensitive behavior Date: October 13, 2021 Source: Hokkaido University Summary: Direct evidence that microtubules function as mechano-sensors and regulate the ...

Crosstalk between actin and microtubules promotes symmetry break to polarize cells for division, shape changes, and migration. CytoPainter Phalloidin-iFluor 488 Reagent Other colors available ...

Building a house without blueprints. Microtubules are the bricks and mortar of the cell, used to build cell walls and the spindles of mitosis and meiosis—without them, even single-celled ...

Some stabilized microtubules are known to have an expanded structure in which the distance between tubulins is greater than that of normal microtubules. And within CAMSAP3, a region called D2 ...

Published: October 6, 2005. By LOIS BAKER Contributing Editor. Neuroscientists at UB have shown in two recently published papers that destabilization of structures called microtubules—intracellular ...

However, the molecular mechanism by which tubulin acetyltransferases modify microtubules and interact with paclitaxel remains unknown. There is an urgent need for research to clarify these ...