Levels of caspase-3 protein expression in various breast cancer cell lines were detected using Western blot analysis. Sixty micrograms of sample protein was applied in each lane and fractionated ...

We hypothesized that the loss of the expression of p27 in nuclei coupled with increased expression of activated caspase 3 in bladder carcinoma-in-situ cells correlates with the subsequent ...

Sequential cleavage/activation of caspase cascades are key steps in triggering apoptosis. Activated caspases, such as caspase-3, target cytoplasmic and nuclear proteins involved in maintaining ...