Celastrol's potent anti-obesity effects were widely reported in 2015. ... This receptor, which receives signals from the cytokine interleukin 1, ...

The results indicate that celastrol effectively attenuated NO and proinflammatory cytokine production via the inhibition of ERK1/2 phosphorylation and NF-κB activation in LPS-activated microglia.

Scientists discover how anti-viral cytokines can blunt the immune response to tuberculosis. A new collaborative study – recently published in the journal Cellular Immunology - between Trinity ...

Celastrol is an active compound from the root of Tripterygium wilfordii Hook F that shows great potential in the treatment of inflammation, cancer, neurodegeneration, diabetes, and obesity.

May 19, 2010 (New Orleans, Louisiana) — Patterns in immune response to Mycobacterium tuberculosis (TB) might lead to more rapid diagnosis of the infection, according to Duke University ...

Two immune system molecules could form the basis of a new test to quickly detect whether tuberculosis is dormant or active and infectious, U.S. researchers said on Sunday.

Celastrol was found to be one of the best-matched drugs that can restrain the release of the virion particles and ... The production of pro-inflammatory cytokines (IL-1β, IL-6, TNF-α, etc ...

Celastrol is an active compound from the root of Tripterygium wilfordii Hook F that shows great potential in the treatment of inflammation, cancer, neurodegeneration, diabetes, and obesity.