Results: ChemoFx results revealed that among the eleven cancer cell lines, one breast cancer cell line and one lung cancer cell line are nonresponsive, while the remaining nine are responsive to ...

Activated caspase-3 cleaves XIAP and further enhances its activation in a positive ... because cleavage of XIAP was also shown to accompany cisplatin-induced sensitization of melanoma cells ...

Cisplatin has been found to trigger apoptosis by inducing caspase-3 activation and PARP cleavage in ovarian cancer cells. 25, 26 We hypothesized that autophagy-associated cell death and autophagy ...

Forsythiae Fructus attenuates cisplatin-induced cytotoxicity in IEC-6 cells and J774A.1 macrophages by inhibiting NLRP3/caspase-1/GSDMD mediated pyroptosis Article Publication Date 29-Oct-2023 ...

Caspase-1 triggers programmed necrosis called pyroptosis by gasdermin-D (GSDMD) cleavage. GSDMD-deficient cells are, however, susceptible to caspase-1-mediated cell death. Researchers at Kanazawa ...