Caspase-3 activation and generation of the caspase-cleaved fragment APPΔC31 within neurons induced by serum deprivation. Neurally differentiated NT2 cells (NT2 neurons) were cultured for 96 h in ...

Interestingly, tau is a known caspase-3 substrate, and caspase-cleaved tau fragments readily form neurofibrillary tangles (see de Calignon et al., 2010). A Slow Death. In this model, increasing ...

At the same time, ICW results showed that cleaved caspase-3 level increased significantly in all of the nine responsive cell lines, but not in the two nonresponsive cell lines. Furthermore, among the ...

In contrast, 17 of the 20 patients in whom invasive bladder cancer did not develop had low levels of activated caspase 3 on immunostaining and high levels of nuclear p27 (sensitivity, 78 percent ...