These are exciting times for biotech business Complement Therapeutics, which stands on the cusp of an important milestone in ...

An international study led by researchers at the University of Colorado Anschutz Medical Campus has identified a promising ...

As Brenner explains, leaking blood vessels allow complement proteins to target brain tissue, causing the immune system to mistakenly launch an attack on the body's own cells and worsen patient ...

Complement 3 glomerulopathy (C3G) and immunoglobulin A nephropathy (IgAN) are two rare types of kidney disease caused by underlying immune system activity.

The immune system has evolved to act as a first responder against infections, and scientists have revealed how it knows when to activate.

The complement receptor 1 (CR1) gene encodes a transmembrane glycoprotein that functions in the innate immune system. CR1 is expressed on blood cells and microglia. As a receptor for the complement ...

Activation of the complement system kicks off a cascade of reactions that recruits immune cells to the site of an infection, flags pathogens for destruction, or even destroys microbes by poking ...

The immune system has traditionally been divided into innate and adaptive components, ... which initiates the complement cascade by cleaving the C3 protein.

Recent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene transfer—activation of the complement system. A new article in ...

Complement responses may contribute to priming of the adaptive immune system or serious adverse ... The authors provide a comprehensive review of the complement cascade with a focus on ...