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Cyclin-dependent kinases (cdks) are critical regulators of cell cycle progression and RNA transcription. A variety of genetic and epigenetic events cause universal overactivity of the cell cycle cdks ...
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IFLScience on MSNWe May Finally Understand Many Cancers' Weak Point As Long-Standing Mystery SolvedMalfunctioning of the enzyme CDK7 is crucial to many cancers, making drugs that target it a high priority. Despite some demonstrated success, the mechanism by which these drugs work has been a mystery ...
Cyclin B-dependent kinase 1 (Cdk1) is a key regulator of mitotic entry 26,27 and little is known about its role in the separation of sister chromatids.
RNA polymerase II (pol II) frequently pauses in the promoter-proximal region to ensure gene-specific regulation and RNA quality control. New research demonstrates that the cyclin-dependent kinase ...
Preliminary results of an observational clinical trial underway at Roswell Park Comprehensive Cancer Center are shedding light on why some patients with an aggressive form of metastatic breast cancer ...
Cyclin-Dependent Kinase 4/6 Inhibitors in the Treatment of Breast Cancer: More Breakthroughs and an Embarrassment of Riches. JCO 35 , 2857-2859 (2017). DOI: 10.1200/JCO.2017.73.9375 ...
Proteotype Diagnostics Ltd and collaborators today announce a breakthrough in early cancer detection and treatment monitoring with the publication of their open-access seminal paper, "Immunodiagnostic ...
Please use one of the following formats to cite this article in your essay, paper or report: APA. Mathur, Neha. (2023, May 14). Investigating the role of cyclins and cyclin-dependent kinases in ...
Cedilla Therapeutics Inc. has synthesized cyclin-dependent kinase 2 (CDK2)/cyclin E1 inhibitors reported to be useful for the treatment of cancer, autoimmune diseases, Cushing syndrome, Alzheimer's ...
Around 5,700 people with early breast cancer are set to benefit from expanded access to a treatment combination designed to help prevent their cancer from returning, following our recommendation, ...
A "pocket" on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct order. Two studies by researchers at the University of Konstanz ...
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