The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...

A discovery that may improve treatment options for patients with neurodegenerative diseases has been made by scientists at King's College London and the University of Bath in the UK.

Aggregation of TDP-43 in the cytoplasm is caused by another protein aggregating in the nucleus, a cytoplasm-based protein called charged multivesicular body protein 7 (CHMP7). Too much CHMP7 in the ...

The neuron uses a multi-tiered strategy to suppress the ... originally identified for their role in cell cycle progression seem to perform essential functions in the neuronal cytoplasm and, ...

Researchers at the Francis Crick Institute and UCL have shown that genetic messages are misplaced in nerve cells in a model of Alzheimer's disease and frontotemporal dementia. These messages ...