New research has uncovered more about the complexity of human gene regulation by identifying certain sequences of proteins ...

A research team has unveiled a crucial mechanism that helps regulate DNA damage repair, with important implications for ...

We often take facts we learn — like the fact that transcription factors bind to DNA — for granted. Or maybe not. See how researchers used DNA footprinting and gel shift assays to prove this idea.

Deep learning and ATAC-seq uncover noncoding variants linked to gene regulation and disease in human liver cells.

Researchers from Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of ...

The transcription factor IID complex locks onto DNA, checks it's in the right place and then recruits other proteins to start transcribing DNA into RNA. New advances in cryo-EM allowed researchers ...

Complex DNA-breakage events such as chromosomal shattering ... human epidermal growth factor receptor 2 (HER2)–positive breast cancer, and squamous-cell carcinoma of the lung.

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease ...