In a new study, researchers describe how a death receptor pathway in the cancer cell itself plays a central role in determining its response to CAR T cells.

Death receptors, belonging to the TNF receptor superfamily, induce apoptosis through two different pathways, one involving the effector caspases directly (type I cells or mitochondria-independent ...

Cell-death Receptor Links Cancer Susceptibility And Inflammation. ScienceDaily . Retrieved June 4, 2025 from www.sciencedaily.com / releases / 2007 / 12 / 071227183749.htm ...

Tumor suppressor protein Par-4 found to trigger unique cell death pathway in cancer cells. Story by Science X staff • 10mo. ... through the nuclear receptor co-activator 4 (NCOA4).

In a review article published in the June 2009 print issue of the FASEB Journal, scientists from the Mayo Clinic explain how cell receptors (called "death receptors") used by the body to shut down ...

To unravel programmed cell death pathways, investigators examine a molecule deemed unimportant, and find new function. Cellular death is vital for health. Without it, we could develop autoimmune ...

Scientists have long been aware that the CD95 receptor, known as Fas, holds the key to killing cells - it's often called a "death receptor." But until now, researchers say, they haven't been able ...

Scientists have discovered tumors can tap a nontraditional pathway to acquire ... Ph.D., postdoctoral fellow, found cancer cells don't rely on usual receptors to ... a type of cell death ...

A team of researchers at NYU Abu Dhabi, led by Professor Sehamuddin Galadari, has discovered that the tumor suppressor protein Prostate apoptosis response-4 (Par-4) can cause a unique type of cell ...