Research published in the Journal of Neurochemistry has detailed the role of a protein, hnRNP A1, in the formation and ...

Their experiments in mouse models of Alzheimer's uncovered TLR7 as a driver of inflammatory demyelination especially in males, but also showed that removing or inhibiting this immune protein can ...

Many of the therapeutic approaches targeting pathogenic T–cell responses in EAE models have not yet translated ... independent mechanisms of autoimmune demyelination exist, our study highlights ...

The UAB Center for Pediatric-Onset Demyelinating Disease (CPODD) is one of the founding Pediatric Multiple Sclerosis (MS) Centers of Excellence in the country designated and funded in 2006 by the ...

Chronic inflammatory demyelinating polyneuropathy is an immune-mediated neuropathy that affects the peripheral motor and sensory nerves. The symptoms are of a slowly progressive numbness and tingling ...

The group used a rodent (murine) model that has also been studied in cases of multiple sclerosis, a disease characterized by severe demyelination. From the eighth week of the experiment ...

Study uncovers how the protein hnRNP A1 may impact myelin stability, offering new clues in schizophrenia development.