Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such ...

This study reports the important development and characterization of next-generation analogs of the molecule AA263, which was previously identified for its ability to promote adaptive ER proteostasis ...

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such ...

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such a clever manner that they raise a red flag as they die. They signal to the ...

The peripheral endoplasmic reticulum (ER) forms a continuous, dynamic network of tubules that plays an important role in protein transport and quality control, cellular signaling, and stress response.

We may earn commission if you buy from a link. Why Trust Us? Here’s what you’ll learn when you read this story: Hemifusomes ...

TorsinA is an AAA+ ATPase located within the lumen of the endoplasmic reticulum and nuclear envelope, with a mutant form causing early onset torsion dystonia (DYT1). Here we report a new function ...

Several studies have shown that the gene encoding endoplasmic reticulum aminopeptidase 1 (ERAP1) is associated with ankylosing spondylitis (AS). ERAP1 and the closely related ERAP2 are involved in ...

The endoplasmic reticulum plays a more important role in type 2 diabetes and its complications than previously believed, new research suggests. To make their discovery, scientists identified ...

All the latest science news on endoplasmic reticulum from Phys.org. Find the latest news, advancements, and breakthroughs.

Human eggs are some of the most patient cells in the body, lying dormant for decades until needed. A study published today in The EMBO Journal shows that the cells deliberately slow the activity of ...

Paul Victor, Dhamodharan Umapathy, Leema George, Udyama Juttada, Goutham V. Ganesh, Karan Naresh Amin, Vijay Viswanathan, Kunka Mohanram Ramkumar, Crosstalk between endoplasmic reticulum stress and ...