º Epinephrine (1:1000 solution) IM, 0.01mg/kg per dose; max 0.5mg per dose (anterior-lateral thigh) º May need to repeat epinephrine dose every 5–15min Adjunctive Treatment ...

146 patients (86.4%) received epinephrine, with 51 (30.1%) receiving it prior to arrival at the hospital and 16 (9.5%) requiring more than one dose. 17 infant patients (10.1%) were admitted to the ...

Subsequently, however, multiple studies in adults, children, and animals failed to show improved outcomes with high-dose epinephrine as compared with standard-dose epinephrine. 1,6,14–22 ...

The US Food and Drug Administration approved the first nasal spray epinephrine drug for severe allergic reactions known as anaphylaxis, providing a needle-free alternative to EpiPens and similar ...