The figure provides an overview of the diverse types of secreted factor contributing to intercellular signalling. Abbreviations: circRNA, circular RNA; lncRNA, ... sequences in extracellular space.

Conditions producing a lack of oxygen, such as stroke, shrink the extracellular space. As the space constricts, the diffusion of substances between cells slows, and toxic substances are ...

Now that the researchers have shown that intercellular flow determines how tissues will adapt to physical forces, these new insights can be applied to understand a wide range of physiological ...

The smooth transportation of substances through the brain extracellular space (ECS) is crucial to maintaining brain function; however, the way this occurs under simulated microgravity remains unclear.

Extracellular vesicles (EVs), including exosomes and microvesicles, play a crucial role in intercellular communication by transferring biomolecules such as proteins, lipids, and RNA.

Extracellular vesicles (EVs) were once thought to be nothing more than cellular debris, but research has previously found that they play a role in mediating intercellular communication. Now, a team of ...

More information: Yosuke Yoneyama et al, Intercellular mRNA transfer alters the human pluripotent stem cell state, Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas ...

Extracellular vesicles and exosomes range tremendously in size, from 30 nanometers—approximately the diameter of a small virus—to as large as one micron.