ATP synthase can be thought of as a complex of two motors — the ATP-driven F1 motor and the proton-driven Fo motor — that rotate in opposite directions. The mechanisms by which rotation and ...

The actual rotational speed of the ATP synthase without an attached actin filament is an amazing 100 revolutions per second. So far only the upper motor, which synthesizes ATP has been observed. Now ...

Okuno D, Iino R and Noji H “Rotation and structure of F0F1-ATP synthase” J Biochem. 2011 Jun; 149(6): 655-64. Last Updated: Feb 26, 2019 Written by ...

The chemical ATP, adenosine triphosphate, is the fuel that powers all life. Despite ATP's central role, the structure of the enzyme generating ATP, F1Fo-ATP synthase, in mammals, including humans ...

With no known treatments for mitochondrial diseases or ATP synthase deficiency, the use of muropeptides as an ATP agonist is a significant discovery. Recent advances in the understanding of the ...

Since raising the activity of ATP synthase may boost mitochondrial respiration and energy production, a chemical agonist of ATP synthase would have high therapeutic potential in this regard.