Cryo-EM structures reveal how the DNA polymerase of herpes simplex virus interacts with DNA and antiviral drugs.

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The Y-family DNA polymerases have unique features that enable them to synthesize DNA past damaged bases, a process known as translesion synthesis. As these polymerases copy undamaged DNA with low ...

DNA polymerase adds new free nucleotides to the 3’ end of the newly-forming strand, elongating it in a 5’ to 3’ direction. However, DNA polymerase cannot begin forming this new chain on its ...

Polymerase A polymerase (EC 2.7.7.6/7/19/48/49) is an enzyme whose central function is associated with polymers of nucleic acids such as RNA and DNA.

RNA polymerase motors down the DNA chain, reading the code of DNA "letters" as it transcribes instructions into RNA molecules, which then direct protein building.

Using this platform, the researchers designed an ultra-high-throughput screening protocol for Bst DNA polymerase based on fluorescence-activated single-cell microfluidics.

The misunderstood polymerase theta has been shown to be able to read RNA back into DNA in mammalian cells, up-ending scientific dogma.

Since DNA polymerase only adds new bases to the 3' end of a DNA molecule, that means it can only copy the bottom strand by starting from a primer at the right, and moving to the left; the opposite ...

Researchers find that the DNA polymerase Taq is not as accurate as was once thought, giving new insight into the dynamics of DNA replication.

Polymerase function during DNA replication DNA polymerase enzymes typically work in a pairwise fashion; each enzyme replicates one of the two strands that comprise the DNA double helix.