Figure 1: Structure of FRα bound to folic acid. Figure 3: Folic acid affinities of FRα ligand-binding-pocket mutants. In summary, many cancers highly express FRα, which has therefore become an ...

“Folic acid is the synthetic version of a B vitamin [B9] that’s needed to form red blood cells. It occurs naturally in food in a form called folate,” says Dr Harriet Bradley, medical ...