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Interferon-γ production by Tfh cells is required for CXCR3+ pre-memory B cell differentiation and subsequent lung-resident memory B cell responses. Immunity , 2023; DOI: 10.1016/j.immuni.2023.08.015 ...
Although a number of studies have recognized that follicular lymphomas may be accompanied by a prominent proliferation of monocytoid B-cells, the clonal relationship between these components has ...
B cell non-Hodgkin lymphoma is a form of cancer that affects immune cells ... After DLBCL, follicular lymphomas make up most cases of B-cell NHLs. This article will review what causes non ...
Malignant B cells in follicular lymphoma clearly play a defining role regarding the composition and function of the tumor microenvironment. The data presented confirm that malignant B cells promote a ...
Update: B-Cell and Follicular Lymphoma ... investigators identified several risk factors for histological transformation of follicular lymphoma in a recent secondary analysis.
Fan pattern D, so-called T-cell-rich nodular pattern: LP cells distribute in a vaguely nodular pattern, but normal follicular B-cells are lost, and the atypical nodules are rich in T-cells. FDC ...
After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have ...
Intact B-cell follicles sequester T follicular helper cells (orange) and latent HIV-infected cells (red) from CD8+ cytotoxic T cells (yellow). CAR T-cell disruption of B-cell follicles allowed these ...
Single-cell sequencing reveals heterogeneous B cell subsets, including plasma cells, follicular B cells, and cytotoxic "killer B cells," each with distinct roles.
André Ballesteros-Tato, Ph.D., and colleagues at the University of Alabama at Birmingham have now published a mouse-model study in the journal Immunity showing that interferon-gamma produced by T ...
Follicular lymphoma is much less common in children than adults, but it does present in unique ways that community oncologists could benefit from recognizing, says Brian Hill, MD, PhD, of ...