Members of the Frat/GBP family of glycogen synthase kinase 3β (Gsk3b)-binding oncoproteins are recognized as potent activators of the Wnt/β-catenin pathway in vertebrates.

The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a village: a combination of physical barriers, chemical attacks, and an army of ...

Research has identified the first inter-species signaling pathway between an arthropod parasite and host, where molecules in the blood of a host animal triggers the immunity and development of a ...

The pathway by which blood cells release the important signalling lipid, sphingosine-1-phosphate (S1P), has now been discovered. They showed that the membrane protein Mfsd2b is responsible for ...

By creating artificial aging in mice, researchers at Lund University in Sweden have been able to track the formation of ...

Melanoma subpopulations that rapidly escape MAPK pathway inhibition incur DNA damage and rely on stress signalling (Nature Communications 2021) ...