DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

Researchers at the Yale School of Public Health have discovered the evolutionary rhythm of gene expression, showing that ...

Central dogma: The clinical view ... makes it clear that any form of current classical one-by-one gene status assessment will not be adequately informative ... accommodating the actual vast ...

University of Buffalo researchers conducted a systematic analysis of switch-like genes by analyzing genomes, transcriptomes ...

In 1958, five years after he helped discover the double helix structure of DNA, Francis Crick coined the term "Central Dogma" to characterize the all-important cellular processes whereby DNA is ...

The central dogma of molecular biology suggests that the primary role of RNA is to convert the information stored in DNA into proteins. In reality, there is much more to the RNA story. 4.2 ...

That could result in the activation of a gene, a halt in gene activity or a sequence that codes for the creation of a ...

But its location and effect on gene expression reflect a new form of epitranscriptome control and suggest an even larger cellular “control panel.” “The discovery of m1A is extremely important, not ...

The finding seems to violate a tenet of genetics so fundamental that scientists call it the central dogma: DNA letters encode information and RNA is made in DNA’s likeness. The RNA then serves ...

Manipulating Gene Expression to Treat Disease. Several of our scientists study gene regulation in specific cancers, including cancers of the blood, lung, pancreas and prostate. They seek treatment ...