The hedgehog (Hh) signaling pathway regulates the differentiation and growth of numerous cell types, including chondrocytes, and thus is essential for normal skeletal development. Pharmacological ...

Several components of the hedgehog (Hh) pathway are crucial to basal cell carcinoma (BCC) tumorigenesis. Primary cilia have emerged as key organelles in Hh signal transduction in mammalian systems ...

Sol-Gel Technologies (SLGL) entered into a product purchase agreement with a subsidiary of Mayne Pharma Group (MAYNF) for the sale and ...

The aPKCi inhibitor platform targets a group of cancers linked to the hedgehog signaling pathway, including basal cell carcinoma, medulloblastoma, small cell lung cancer, rhabdomyosarcoma ...