Research by Takebe et al. demonstrated that vascularised liver organoids derived from induced pluripotent stem cells (iPSCs) ...

Our liver assembloids are the first all-in-one lab model that can be used to study bile flow, bile duct injury, and how different liver cells contribute to disease.” ...

Scientists have learned more about a genetic disorder that affects the liver; the work also reveals potential new therapeutic avenues for treating the disease, Alagille syndrome. The researchers, from ...

They developed a predictive 3D multi-scale model that can simulate the fluid dynamics of bile. Although the model currently only represents the network of bile ducts in the mouse liver, the ...

Using mutant zebrafish, the research team discovered that Jagged signals come from an unexpected cell type, endoderm-derived cells within the liver itself, stimulating duct cell identity in the liver.

Bile duct inflammation and scarring, known as cholangiopathies, can disrupt bile flow, leading to liver damage and potentially liver failure. Bile Duct Inflammation and Scarring: Causes, Diagnosis ...

Bile duct cancer is also known as cholangiocarcinoma. There are 3 types of bile duct cancer. The type depends on where in the bile ducts the cancer starts. Perihilar bile duct cancer starts in the ...

Bile duct cancer is a disease where cancerous cells form in the tissues of the bile duct. The bile duct is part of a network of tubes that connect the liver, gallbladder, pancreas, and small intestine ...

To the point. New tissue-derived organoid model: A next-generation organoid model, composed of three liver cell types – adult hepatocytes, cholangiocytes, and liver mesenchymal cells – reconstructs ...