that affects the enzyme cystathionine beta-synthase (CBS), which is essential for metabolizing homocysteine. The study ...

Without the conversion, rising homocysteine levels interfere with the folding and structure of collagen, a component of bone, tissue and the basement membrane of blood vessel walls.

In observational studies, lower homocysteine levels are associated with lower rates of coronary heart disease and stroke. Folic acid and vitamins B6 and B12 lower homocysteine levels. We assessed w ...

High homocysteine levels may indicate a vitamin deficiency and the chance of developing other conditions. Learn more about what high homocysteine levels mean.

The high plasma levels of homocysteine in some lupus patients may cause endothelial cell damage, trigger platelet activation, and contribute to the increased rate of cardiovascular disease ...

A homocysteine level in the highest age-specific quartile was associated with an increase by a factor of 1.9 in the risk of fracture (95 percent confidence interval, 1.4 to 2.6).

What approach should be used to treat an elevated homocysteine level that is unresponsive to folic acid, vitamin B6, and vitamin B12? News & Perspective Drugs & Diseases ...

Research indicates that an elevated homocysteine level is a greater […] Skip to content. All Sections. Subscribe Now °F. Friday, February 14th 2025 e-Edition. Home Page. Close Menu.

Methylenetetrahydrofolate reductase (MTHFR) is an enzyme that breaks down the amino acid homocysteine. If the MTHFR gene that codes for this enzyme mutates, it may contribute to a variety of ...

Objective: Elevated levels of plasma total homocysteine (tHcy) are identified as independent risk factors for coronary heart disease and for fetal neural tube defects. tHcy levels are negatively ...