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Learn about the symptoms and causes of hypophosphatemia. Berger MM, et al. (2020). Prevalence of hypophosphatemia in the ICU – Results of an international one-day point prevalence survey. https ...
These authors recommended parenteral therapy for all causes of hypophosphatemia, at an initial dose of 0.08 mmol/kg body weight (2.5 mg/kg body weight) if the onset was recent and the case ...
The effects of hypophosphatemia may be broad and can affect nearly every body system. Symptoms may only become apparent at serum phosphate levels below 0.32 millimoles per liter (mmol/L).
Moderate hypophosphatemia (1.0-2.5 mg/dl [0.3-0.8 mmol/l]) in nonventilated patients should be managed with oral replacement therapy (1,000 mg/day) Mild hypophosphatemia should be managed with ...
Abnormal bony projections in joint spaces and at attachments of tendons or ligaments were common among a small cohort of middle-aged adults with X-linked hypophosphatemia, progressively impairing ...
There are several reasons patients with multiple myeloma may experience the electrolyte abnormality. A new literature review assessed the causes and consequences of hypophosphatemia in patients ...
According to analysis, hypophosphatemia was reported in 8.3% of patients in the FDI group and 51% of patients in the FCM group (adjusted risk difference = –42.8%; 95% CI, –57.1 to –24.6).
Burosumab is a recombinant human IgG1 monoclonal antibody that targets FGF-23. 13,14 In phase 1 and 2 trials involving adults with X-linked hypophosphatemia, treatment with burosumab, administered ...
Hypophosphatemia affects the entire body, even on an intracellular level. If gone untreated, it can result in: Bone diseases like rickets, osteopenia, osteoporosis, and osteomalacia; ...