Intravenous bolus fluorouracil plus leucovorin is the standard adjuvant treatment for colon cancer. The oral fluoropyrimidine capecitabine is an established alternative to bolus fluorouracil plus l ...

The choice of IV loading bolus 5-FU/leucovorin as the parenteral comparison regimen, which was apparently mandated by regulatory agencies, resulted in a far higher rate of stomatitis and ...

Secondary carnitine deficiency: 50mg/kg as slow (2–3mins) IV bolus inj or infusion; usual max 300mg/kg. May give loading dose in severe metabolic crisis: see full labeling.

Intelliport System Cleared to Improve IV Bolus Management BD announced that the Food and Drug Administration (FDA) has cleared the BD Intelliport Medication Management System, a management system ...

Key takeaways: TNKase is the first stroke treatment approved by the FDA in almost 30 years, the manufacturer said. It is approved for administration as a single 5-second IV bolus.

Leipzig and Berlin, Germany - In the setting of acute ST-elevation MI (STEMI) treated with PCI, giving the initial bolus of abciximab (ReoPro, Eli Lilly/Centocor) by the intracoronary (IC) route ...

Can an amiodarone drip be converted to twice-daily IV bolus dosing if the patient is unable to take anything by mouth or nasogastric tube? In conclusion, on the basis of the pharmacokinetic ...

The Subject Expert Committee (SEC) under the Central Drugs Standard Control Organisation (CDSCO) has declined to approve ...

Delivered as a once-daily 30 mg/mL IV bolus injection over 15 seconds, Xifyrm can be used alone or alongside non-NSAID analgesics as part of a multimodal pain strategy. The FDA has approved Azurity ...

After endoscopic treatment, patients were randomly assigned to receive an intravenous infusion of placebo or omeprazole (Losec, Astra, Mölndal, Sweden), given as an 80-mg bolus injection followed ...

Alteplase (Actilyse, recombinant human tissue plasminogen activator, rtPA) can be delivered in a standard or accelerated regimen. The accelerated regimen, which is much more commonly used, is ...

Flavopiridol induces apoptosis in CLL cells in a p53-independent manner, but phase I/II studies using a 24–72-hr CIVI schedule showed no activity. Increased drug binding to human plasma proteins ...