They exhibited reduced plasma glycerol levels and improved insulin-mediated suppression of hormone-sensitive lipase phosphorylation in white fatty tissues, indicating better regulation of lipolysis.

Insulin-dependent diabetes: a defect in the activity of lipoprotein lipase in adipose tissue Diabetologia 1979 16: 313–317. Article CAS Google Scholar Ryan EA, Enns L .

Interestingly, insulin-stimulated glucose uptake was attenuated by, respectively, 13, 22 and 21% following single ATGL, HSL and double lipase silencing, respectively (all P<0.01, Figure 2a ...

Recently, the enzyme lipoprotein lipase (LPL) has been implicated in the normal physiology of lipemia clearing. 8,9 This enzyme, which appears to be identical with the postheparin-clearing factor ...

GLP-1 promotes insulin secretion in a glucose-dependent manner and preserves pancreatic β-cell function. [] In addition to its proinsulinemic effects, GLP-1 has been shown to have extrapancreatic ...

The absence of intraluminal lipoprotein lipase prevents the lipolytic processing of triglyceride-rich lipoproteins and results in severe hypertriglyceridemia (chylomicronemia, defined as a ...

Long-Term Retrospective Analysis of Gene Therapy with Alipogene Tiparvovec and Its Effect on Lipoprotein Lipase Deficiency-Induced Pancreatitis. Human Gene Therapy , 2016; DOI: 10.1089/hum.2015. ...