Research led by Naval Medical University's Changzheng Hospital in China reports that an off-the-shelf cell therapy built from ...

The measurement of soluble interleukin-2 receptor (sIL-2R) levels in serum or plasma in adults has become a valuable tool for clinicians to assess immune function in vivo as part of the ...

Interleukin-2 and interleukin-15 have pivotal roles in the control of the life and death of lymphocytes. Although their heterotrimeric receptors have two receptor subunits in common, these two ...

High serum concentrations of the alpha chain IL-2 receptor are highly correlated with a shorter survival of patients diagnosed with head and neck squamous-cell carcinoma.

Used in combination with antiretroviral therapy, subcutaneous recombinant interleukin-2 raises CD4+ cell counts more than does antiretroviral therapy alone. The clinical implication of these increa ...

The increases in levels of interleukin-6, interferon-γ, CXCL9, and soluble interleukin-2 receptor coincided with the tumor lysis syndrome, peak chimeric antigen receptor T-cell infiltration, and ...

Interleukin-2 (IL-2) inhibitors are immunosuppressive agents that block the activity of IL-2, a cytokine involved in the activation and proliferation ...

To compare the value of soluble interleukin 2 receptor (sIL-2R) with ACE as diagnostic biomarkers of sarcoidosis in patients with uveitis.

Interleukin-2 (IL-2) is a cytokine that is critical to the regulation of T-cell responses. IL-2 also has a huge range of immunostimulatory and immunomodulatory functions.

REZOLVE-AD, the phase 2b study, is set to investigate the efficacy and safety of rezpegaldesleukin, a first-in-class interleukin-2 receptor agonist that proliferates and activates regulatory T ...

Yet that same stimulation is known to induce expression of the interleukin-2 receptor and production of the interleukin IL-2, which together should create a feedback loop of IL-2 signaling that is ...