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Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis. Science , March 2015 DOI: 10.1126/science.aaa4268] Cite This Page : ...
Interleukin-3 (IL-3) can promote the development of various hematopoietic cells in vitro, through effects on both multipotential and more mature, lineage-committed progenitor cells. 1 While many ...
Interleukin Interlocutor. IL-3 facilitates cross-talk between astrocytes and microglia. The interleukin triggers the latter to surround and clear amyloid plaques. [Courtesy of Barron and Molofsky, ...
A 3-week interval was achieved in 62% of cycles and a 4-week interval in 81%, with no difference between the rhIL-3 doses. A neutrophil nadir less than 0.5 x 10(9)/L occurred in 35% of the cycles at 5 ...
The goal of this study was to explore immunological strategies to increase local and systemic tumor control in patients receiving radiation therapy. In previous studies, interleukin-3 (IL-3) gene ...
PURPOSETo determine whether recombinant human interleukin-3 (rhIL-3) reduces bone marrow depression and improves chemotherapeutic schedule adherence in ovarian cancer patients receiving first-line ...
Interleukin-2 (IL-2) inhibitors are immunosuppressive agents that block the activity of IL-2, a cytokine involved in the activation and proliferation of T cells. The growing prevalence of autoimmune ...
A large, prospective study implicates high levels of interleukin 6 with severity of diabetic retinopathy and shows it may be ...
The messenger substance interleukin-3 produced by the body was previously considered to be pro-inflammatory in bronchial asthma. A research team from Universitätsklinikum Erlangen has now shown ...
Interleukin-2 is critical for Treg-cell development, expansion, activity, and survival. 20,21 In patients who do not have GVHD after undergoing HSCT with T-cell depletion, treatment with low-dose ...
Interleukin-2 has been identified for its capacity to stimulate T cells in vitro 1 and has been used to boost effector immune responses in patients with cancers and infectious diseases. 2,3 It is ...