Regulatory T cells police the immune system, making sure that killer T cells coming back from battling pathogens transition into a resting state, but still prepared to fight if the pathogen returns.

Unlike other killer T cells, these home in on multiple cancer-associated targets at once, preventing new tumors forming for up to a year later and could lead to more effective cancer therapies.

Natural killer T cells possess innate-like properties that make them uniquely equipped to fight solid tumors. Specifically, they express a T cell receptor that recognizes glycolipid antigens ...

Further study is needed to determine whether rogue killer T cells are involved in all autoimmune diseases, and what proportion of people with rheumatoid arthritis and other autoimmune conditions ...

Scientists at the University of Virginia School of Medicine have discovered a defect in immune cells known as "killer T cells" that explains their inability to destroy cancer tumors. The ...

Killer T cells, as their name might imply, are not known for their mercy. When these immunological assassins happen upon a cell that’s been hijacked by a virus, their first instinct is to butcher.

In the case of COVID-19, killer T cells could mean the difference between a mild infection and a severe one that requires hospital treatment, says Annika Karlsson, ...

The gene therapy known as CAR-T uses a patient's own T-cells to target and kill malignancies. The therapy, which has been researched for decades, is now proving effective at turning sick patients ...

After testing different methods to observe how CD36 impaired killer T cell function, researchers created mouse models lacking CD36 on T cells and used antibodies to block CD36.

T cells are white blood cells that flare up when the body is infected with a virus. They attack the cells that are already infected and get rid of them, so the body can stay healthy.

CAR-redirected natural killer T cells demonstrate superior antitumor activity to CAR-T cells through multimodal CD1d-dependent mechanisms. Nature Cancer, 2024; DOI: 10.1038/s43018-024-00830-0; ...