With the help of several autophagy-related (ATG) proteins, a small, ubiquitin-like protein called LC3 (LC3-II when bound) binds the nascent phagophore to direct its expansion around cytoplasmic ...

Autophagy is a cellular process performed by cells for degradation and recycling. ... Secondly, LC3 is cleaved by the protease Atg4 and binds to the lipid phosphatidylethanolamine ...

Autophagy is defined as regulated self-eating that occurs through the degradation of cellular components. ... (LC3) subfamily and the γ-aminobutyric acid receptor-associated protein (GABARAP ...