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Autophagy is defined as regulated self-eating that occurs through the degradation of cellular components. It is an important response to cellular starvation.
Diminished platelet autophagy potentially contributes to thrombocytopenia in cirrhotic patients. H 2 S modulates platelet autophagy and functions possibly via the PDGFR-α/PI3K/Akt/mTOR signaling ...
Researchers conducted clinical studies on murine animals and humans to evaluate the impact of high protein intake on the amino acid-mammalian target of the rapamycin complex 1 autophagy signaling ...
In their study, the researchers revealed that an autophagy pathway in astrocytes (non-neuronal cells in the brain) removes amyloid-beta (Aβ) oligomers, the toxic proteins found in the brains of ...
The researchers used fluorescently tagged LC3 to track the autophagy process, and demonstrated that 6-OHDA treatment increased autophagosome formation and enhanced autophagosome-lysosome fusion ...