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Does MYC binding to chromatin serve transcription-independent functions, including the regulation of chromosomal integrity, gene expression, chromatin structure, cellular replication and genomic ...
A review paper published last year in European Journal of Medicinal Chemistry characterized Myc as the “oncogene from ...
Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein ...
The MYC gene is a regulatory and proto-oncogenic gene that is overexpressed in the majority of prostate cancers (PCa). Numerous studies have indicated that aberrant expression of microRNAs is ...
Therapy-related B-lymphoblastic leukemia (B-ALL) following treatment for multiple myeloma is a rare occurrence.
Researchers at Karolinska Institutet identified a super-enhancer region upstream of the MYC gene essential for tumor development and tissue repair. Cancer has often been described as a wound that ...
The tiny strings of RNA promote translation of a protein implicated in cancer, a hint they could regulate gene expression in more ways than previously thought. Holly Barker is a freelance journalist ...