Deletion mutants are able to transform Rat-1A cells. Within this region MYC is highly regulated through phosphorylation of Thr58 and Ser62. MYC homology box II (aa 128–143) This domain is ...

Inhibiting RMB42 disrupted production of Myc proteins in pancreatic cancer cells. This approach could curtail the growth of several cancer types. A review paper published last year in European ...