Researchers have developed a peptide that targets a protein implicated in 75% of human cancers and found that it slowed the proliferation of cancer cells in the lab. It’s the first step towards ...

Like any protein, MYC is built using the instructions that are stored in the MYC gene. First, in a process called transcription, the cell uses these instructions to make a blueprint, called mRNA. Then ...

Meet MYC, the shapeless protein responsible for making the majority of human cancer cases worse. UC Riverside researchers have found a way to rein it in, offering hope for a new era of treatments.

MYC proteins play an important role in many types of cancer. A research team at the University of Würzburg has now succeeded in indirectly influencing these proteins - with clear consequences for ...

The MYC proteins (grey ribbons) bind to DNA and promote cancer progression. UCR researchers developed a molecule (orange pretzel-like shape) that binds to MYC, inhibiting its cancer-promoting ...

However, the shapeless protein is responsible for making the majority of human cancer cases worse. Finding a way to control MYC is challenging because unlike most other proteins, MYC has no structure.

By targeting the c-MYC mRNA with small molecules, Ribometrix is bypassing the “undruggable” challenges to successfully reduce c-MYC protein levels and develop a novel anti-cancer therapeutic ...

They found that a protein called RBM10 can partner with other proteins to stop c-Myc activity, which is a tumor-stimulating protein that causes lung cancers. U.S. World ...

"Because it is so difficult to attack MYC proteins directly, we were looking for partners of MYC and found a protein called SPT5", Elmar Wolf describes the preliminary work for this study.

Scientists identified Myc in the 1970s, and they discovered the protein does not have to be mutated to become cancerous. Instead, it’s the continuous production that makes the protein dangerous.

Expression of myc transcripts and proteins. The indicated cultures were harvested during log-phase growth in 10% serum. TGR-1-(0.25% serum) refers to parental TGR-1 cells which were serum starved ...

Like any protein, MYC is built using the instructions that are stored in the MYC gene. First, in a process called transcription, the cell uses these instructions to make a blueprint, called mRNA.